Perio Intensive Care
When plaque accumulates and brushing is difficult. For example after periodontal and implant surgery, and sutured wounds next to teeth. Used short term, until the patient can brush again.
For professionals
An overview for dentists, hygienists and pharmacists: which product suits which situation, and what the studies say.
Choosing a product
| Situation | Product | Classification |
|---|---|---|
| Localised gingival inflammation within finger reach; early periodontal disease | Gel 0.2% | Medical device IIa |
| Localised gingival inflammation that is hard to reach | Spray 0.01% | Medical device IIa |
| Dry mouth; soreness from chronic friction on thinned mucosa | Spray 0.01%; Forte Spray 0.04% if the mucosa is very sore. Gel or Forte Gel in severe dry mouth, for lubrication and pain relief | Medical device IIa |
| Generalised gingival inflammation, maintenance | Mouthrinse 0.025% | Medical device IIa |
| Lesions from orthodontic appliances | Teen Gel 0.2% | Medical device IIa |
| Teething and minor trauma in infants | Baby Gel 0.54% | Medical device IIa |
| Aphthous ulcers and traumatic lesions; wounds after biopsy and surgery where plaque is not a concern | Forte Gel 0.8%, with long cannula | Medical device IIb |
| Aphthous ulcers and painful traumatic lesions at hard-to-reach sites | Forte Spray 0.04% | Medical device IIa |
| Multiple or diffuse painful lesions, full mucosal coverage | Forte Mouthrinse 0.1% | Medical device IIa |
| Acute phase after surgery when the patient can keep the area clean | First Aid Oral Fluid 0.12% | Medical device IIb |
| After surgery when brushing is difficult and plaque accumulates | Forte Perio Intensive Care (chlorhexidine 0.2%) | Cosmetic |
| Longer-term or daily plaque control | Perio Long-Term Care (0.12%), Perio Gentle Care (0.05%) | Cosmetic |
| Daily brushing for sensitive gums | Gum Protection toothpaste 0.06%, with fluoride | Cosmetic |
After surgery: Forte or Perio?
Hyaluronic acid supports healing and eases pain but has little effect on plaque. Chlorhexidine controls plaque but does not promote healing. The choice therefore depends on whether the patient can keep the area clean.
Forte
When plaque is not a concern, or in combination with chlorhexidine products. For example after a biopsy and other wounds of the oral lining away from the teeth. It does not stain teeth or disturb taste, so it can be used for as long as needed.
Together: Forte with chlorhexidine. The Forte products and First Aid can be used alongside any chlorhexidine product, including where chlorhexidine is already part of the aftercare. The chlorhexidine takes care of plaque, and the hyaluronic acid speeds healing and reduces pain. The patient does not have to choose between them.
A systematic review of 22 clinical studies found significantly less pain seven days after third molar removal with hyaluronic acid, but no effect on swelling or trismus.
Hyaluronic acid in tooth extraction: a systematic review and meta-analysis. Clin Oral Investig 2023.In a randomised trial of 33 patients after periodontal surgery, wounds closed sooner with a rinse containing both chlorhexidine and hyaluronic acid than with no rinse.
Early periodontal wound healing after chlorhexidine rinsing: a randomized clinical trial.Evidence
Topical hyaluronic acid has been studied in gingivitis, as an adjunct to periodontal treatment, in aphthous ulceration and after oral surgery. Many of the studies are small and results vary by indication. A few examples follow.
Gingivitis
Randomised double-blind study of 0.2% gel in plaque-induced gingivitis, applied daily for 21 days.
Jentsch H, Pomowski R, Kundt G, Göcke R. J Clin Periodontol 2003;30:159–164.Adjunct to periodontal treatment
Split-mouth study of 12 patients with chronic periodontitis over 12 weeks, with gel placed subgingivally after debridement.
Johannsen A, Tellefsen M, Wikesjö U, Johannsen G. J Periodontol 2009;80(9):1493–1497.Recurrent aphthous ulcers
Double-blind placebo-controlled study of 120 patients, and a study of 0.2% gel in aphthous ulcers and the oral ulcers of Behçet's disease.
Nolan A et al. J Oral Pathol Med 2006. · Lee JH, Jung JY, Bang D. J Eur Acad Dermatol Venereol 2008;22(5):590–595.After oral surgery
Hyaluronic acid spray compared with benzydamine spray after third molar surgery, and a randomised trial of palatal wound healing.
Koray M et al. Int J Oral Maxillofac Surg 2014;43(11):1399–1403. · Yıldırım S et al. J Periodontol 2017.Implants
Pilot study comparing hyaluronic acid gel with chlorhexidine for implant maintenance in the first months.
de Araújo Nobre M, Cintra N, Maló P. Int J Dent Hyg 2007;5:87–94.Downloads
These documents come from the manufacturer, Ricerfarma, and are in English. The product sheets are intended for healthcare professionals.
Technology and patents
Fact files
Overviews of how oral health relates to various conditions and situations, with references.
Samples and orders
Dental clinics and pharmacies can order directly from us and request samples and information material. Get in touch.